Have you ever wondered how some people manage to stay thin despite eating whatever they like, while others gain weight from just about anything?
The secret of their flawless body is not necessarily in a drastic regimen and an orderly lifestyle, writes Unbeliveble Facts.
A study by a group of researchers from Cambridge found that some people have a unique genetic code that helps them maintain the same body weight throughout their lives. While previous research has focused on the genetic influence on obesity, this recent study has focused on what it means to be thin.
The study, published in the journal PLOS Genetics, is the largest to date. The team compared the DNA of about 14,000 people and divided them into different weight groups to find out how genes can influence how many kilograms a person weighs.
Sadaf Farooqi, professor at the Wellcome-MRC Institute of Metabolic Sciences at the University of Cambridge, led the study, which was funded by the European Research Council. The goal of Thin People and the Study of Thin People was to find out how and why some people have no problem staying thin compared to others.
Previous research has shown that faulty genes are responsible for severe obesity, which often occurs at an early age. This particular study, however, showed that a combination of "lean" genes, or rather the absence of "obesity-related genes", can help a person stay lean.
Human DNA is made up of a sequence of molecules called "base pairs". Our genes dictate how our bodies work, and variations at the base pair level can have subtle or powerful effects on characteristics such as eye color, hair color, and, of course, weight.
The research team found several genetic variants that have already been identified by researchers and are associated with obesity. However, recent research has identified new genetic regions that may be responsible for a healthy silhouette.
To figure out how genes affect someone's weight, the researchers took into account all the genetic variants and came up with a genetic risk scale.
As they suspected, obese people have a higher genetic risk score, which indicates that their risk of becoming overweight is greater than that of normal weight people. On the other hand, thin people have a significantly lower genetic risk score. They also lack genetic variants known to cause obesity. Thus, the study showed that people who have always been thin, despite diet and lifestyle, have a unique genetic makeup. Although genes may determine a person's weight, this does not mean that you should give up a healthy diet and a healthy lifestyle, since personal actions play a decisive role when it comes to weight control /